Predict Alzheimer's Disease up to 10 years in advance

Protocol	Assay Protocol (PDF)
Sample Preparation	Blood collection Plasma extraction Tissue extraction CSF extraction
Catalog #	EK-018-35
Standard Size	96 wells
Sensitivity	Minimum Detectable Concentration = 1.56 ng/ml
Linear Range	1.56-100 ng/ml
Cross Reactivity	Peptide % Cross-Reactivity Clusterin (Human) 100
Standard Curve Image

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Publications Related to Clusterin:

Jones N et al. “Alzheimer disease: Plasma clusterin predicts degree of pathogenesis in AD” Nat Rev Neurol. 2010 Sep;6(9):469.

Lidström A-M et al. “Clusterin (Apolipoprotein J) protein levels are increased in hippocampus and in frontal cortex in Alzheimer’s Disease” Exp Neurol. 1998 Dec;154(2):511-21.

Thambisetty M et al. “Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease” Arch Gen Psychiatry. 2010; 67(7): 739-748

Zheng YL et al. “A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation.” J Biol Chem. 2010 Oct 29;285(44):34202-12.