VIP (Vasoactive Intestinal Peptide /PHI and Related Peptides)

Prepro-VIP/PHM-27 Schematic (Human)

Normal Plasma Peptide/Protein Levels

Protocol	Assay Protocol (PDF)
Sample Preparation	Blood collection Plasma extraction Tissue extraction CSF extraction
Catalog #	RK-064-16
Standard Size	125 RIA tubes
Radioactivity	This kit contains 1.5 µCi of Iodine 125
Range	1-128 pg/tube of 100µl Standard Solution = 10-1280 pg/ml
Lowest Detection Limit	35.5 pg/ml
Cross Reactivity	Peptide % Cross-reactivity  VIP (Human, Porcine, Rat)  100  PACAP-27-NH2 (Human, Rat, Ovine)  0  PHM-27 (Human)  0  Substance P  0  Endothelin-1    (Human, Rat, Porcine, Mouse, Canine, Bovine)  0  Glucagon (Human)  0  Galanin (Rat)  0  Somatostatin  0  PACAP-38 (Human, Rat, Ovine)  0
Sequence	His - Ser - Asp - Ala - Val - Phe - Thr - Asp - Asn - Tyr - Thr - Arg - Leu - Arg - Lys - Gln - Met - Ala - Val - Lys - Lys - Tyr - Leu - Asn - Ser - Ile - Leu - Asn - NH2

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this kit:

Hook et al. Differential activation of enkephalin, galanin, somatostatin, NPY, and VIP neuropeptide production by stimulators of protein kinases A and C in neuroendocrine chromaffin cells.
Neuropeptides. 2008 Oct-Dec;42(5-6):503-11.

Hong et al. Role of vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide in the vaginal wall of women with stress urinary incontinence and pelvic organ prolapse.
Int Urogynecol J Pelvic Floor Dysfunct. 2008 Aug;19(8):1151-7.

Kuncová et al. Chronic atropine administration diminishes the contribution of vasoactive intestinal polypeptide to heart rate regulation.
Physiol Res. 2007 Nov 30. [Epub ahead of print]

Huang et al. Differential signaling of T cell generation of IL-4 by wild-type and short-deletion variant of type 2 G protein-coupled receptor for vasoactive intestinal peptide (VPAC2).
J Immunol. 2006 Jun 1;176(11):6640-6.

Caviedes-Bucheli et al. Quantification of neuropeptides (calcitonin gene-related peptide, substance P, neurokinin A, neuropeptide Y and vasoactive intestinal polypeptide) expressed in healthy and inflamed human dental pulp.
Int Endod J. 2006 May;39(5):394-400.

Dvoráková et al. Down-regulation of vasoactive intestinal peptide and altered expression of its receptors in rat diabetic cardiomyopathy.
Cell Tissue Res. 2006 Mar;323(3):383-93.

Kuncová et al. Distribution of vasoactive intestinal polypeptide in the rat heart: effect of guanethidine and capsaicin.
Ann Anat. 2003 Apr;185(2):153-61.

Voice et al. Roles of Vasoactive Intestinal Peptide (VIP) in the Expression of Different Immune Phenotypes by Wild-Type Mice and T Cell-Targeted Type II VIP Receptor Transgenic Mice.
J Immunol. 2003 Jan 1;170(1):308-14.

Mazzacchi et al. Expression and function of vasoactive intestinal peptide, pituitary adenylate cyclase-activating polypeptide, and their receptors in the human adrenal gland.
J Clin Endocrinol Metab. 2002 Jun;87(6):2575-80.

Netzer et al. Does intravenous ondansetron affect gastric emptying of a solid meal, gastric electrical activity or blood hormone levels in healthy volunteers?
Aliment Pharmacol Ther. 2002 Jan;16(1):119-27.

Sari et al. Impairment by lovastatin of neural relaxation of the rabbit sphincter of Oddi.
Eur J Pharmacol. 2001 Nov 30;432(1):91-7.

Voice JK. - J. Immunol. - Jan 2003; 170: 308 - 314