Amylin

Normal Plasma Peptide/Protein Levels

Protocol	Assay Protocol (PDF)
Sample Preparation	Blood collection Plasma extraction Tissue extraction CSF extraction
Catalog #	RK-017-11
Standard Size	125 RIA tubes
Radioactivity	This kit contains 1.5 µCi of Iodine 125
Range	1-128 pg/tube in 100 μl of Standard Solution = 10-1280 pg/ml
Lowest Detection Limit	58.45 pg/ml
Cross Reactivity	Peptide %Cross-reactivity  Amylin (Rat)  100  Amylin-Amide (Feline)  100  Amylin Amide (Human)  10  CGRP (Human)  0  CGRP (Rat)  0  CGRP II (Human)  0  CGRP II (Rat)  0  Pancreatic Polypeptide (Human)  0  Amylin (Human)  0  Insulin (Human)  0  Pro-Insulin  0  Glucagon (Human)  0  Somatostatin-28  0  Pancreatic Polypeptide (Human)  0  VIP (Human, Rat, Porcine)  0  NPY (Porcine)  0
Sequence	Lys - Cys - Asn - Thr - Ala - Thr - Cys - Ala - Thr - Gln - Arg - Leu - Ala - Asn - Phe - Leu - Val - Arg - Ser - Ser - Asn - Asn - Leu - Gly - Pro - Val - Leu - Pro - Pro - Thr - Asn - Val - Gly - Ser - Asn - Thr - Tyr - NH2 Disulfide Bridge: Between Cyc2 & Cys7

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that used this kit:

Knight, W. David. Cardiovascular and Metabolic Responses to Peripheral Leptin Infusion in Rats: Role of Amylin in Leptin Sensitivity
Ph.D Dissertation, FSU.

Davidowa et al. GABAA receptor antagonists prevent abnormalities in leptin, insulin and amylin actions on paraventricular hypothalamic neurons of overweight rats.
Eur J Neurosci. 2006 Mar;23(5):1248-54.

Brissova et al. Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion.
J Biol Chem. 2002 Mar 29;277(13):11225-32.
in mouse pancreatic extracts: Brissova M. - J. Biol. Chem. - Vol. 277 - Issue 13 - 11225-11232 - March 29 - 2002