DNP (Dendroaspis Natriuretic Peptide)

Normal Plasma Peptide/Protein Levels

Protocol	Assay Protocol (PDF)
Sample Preparation	Blood collection Plasma extraction Tissue extraction CSF extraction
Catalog #	RK-013-01
Standard Size	125 RIA tubes
Radioactivity	This kit contains 1.5 µCi of Iodine 125
Range	10-1280 pg/tube in 100μl of Standard Solution = 100-12800 pg/ml
Lowest Detection Limit	530.75 pg/ml
Cross Reactivity	Peptide   %Cross-reactivity   Dendroaspis Natriuretic Peptide (DNP)  100  a-ANP (1-28) (Human, Canine)  0  Prepro-ANP (26-55) (Human)  0  CNP-22 (Human, Porcine, Rat)  0  BNP-32 (Human)  0
Sequence	Glu - Val - Lys - Tyr - Asp - Pro - Cys - Phe - Gly - His - Lys - Ile - Asp - Arg - Ile - Asn - His - Val - Ser - Asn - Leu - Gly - Cys - Pro - Ser - Leu - Arg - Asp - Pro - Arg - Pro - Asn - Ala - Pro - Ser - Thr - Ser - Ala ~ Disulfide bridge between Cys7 & Cys23

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this kit:

Khurana et al. A pilot study of dendroaspis natriuretic peptide in aneurysmal subarachnoid hemorrhage.
Neurosurgery. 2004 Jul;55(1):69-75; discussion 75-6.

Pan et al. Gene transfer of a novel vasoactive natriuretic peptide stimulates cGMP and lowers blood pressure in mice
Am J Physiol Heart Circ Physiol. 2004 Jun;286(6):H2213-8.

Kim et al. Enhanced Dendroaspis natriuretic peptide immunoreactivity in experimental ureteral obstruction.
Nephron. 2002 Oct;92(2):369-72.

Fábrega et al. Dendroaspis natriuretic peptide in hepatic cirrhosis.
Am J Gastroenterol. 2001 Sep;96(9):2724-9.

Lisy et al. Renal actions of synthetic Dendroaspis natriuretic peptide
Kidney Int. 1999 Aug;56(2):502-8.

Mas-Nieto M. - Br. J. Pharmacol. - Apr 2001; 132: 1809 - 1816