C-type Natriuretic Peptides

Normal Plasma Peptide/Protein Levels

Protocol	Assay Protocol (PDF)
Sample Preparation	Blood collection Plasma extraction Tissue extraction CSF extraction
Catalog #	RK-012-03
Standard Size	125 RIA tubes
Radioactivity	This kit contains 1.5 µCi of Iodine 125
Range	1-128 pg/tube in 100?l of Standard Solution = 10-1280 pg/ml
Lowest Detection Limit	17.9 pg/ml
Cross Reactivity	Peptide %Cross-reactivity CNP-22 (Human, Rat, Mouse, Porcine, Bovine, Monkey) 100 CNP-53 (Human) 100 CNP-53 (1-29) (Rat, Porcine) 0 α-ANP (1-28) (Human, Canine) 0 ANP (Rat) 0 BNP-32 (Porcine) 0 BNP-45 (Rat) 0 Endothelin-1 (Human, Rat, Mouse, Porcine, Bovine, Canine) 0
Sequence	Gly - Leu - Ser - Lys - Gly - Cys - Phe - Gly - Leu - Lys - Leu - Asp - Arg - Ile - Gly - Ser - Met - Ser - Gly - Leu - Gly - Cys ~ Disulfide bridge between Cys6 & Cys22

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this kit:

Del Ry et al. Expression of C-type natriuretic peptide and of its receptor NPR-B in normal and failing heart.
Peptides. 2008 Dec;29(12):2208-15.

Nielsen et al. ProCNP and CNP are expressed primarily in male genital organs.
Regul Pept. 2008 Feb 7;146(1-3):204-12.

Kuo et al. C-type natriuretic peptide in individuals with normal left ventricular systolic function
Scand Cardiovasc J. 2007 Jun;41(3):155-9.

Bocciardi et al. Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation
Hum Mutat. 2007 Jul;28(7):724-31.

Cataliotti et al. CNP production in the kidney and effects of protein intake restriction in nephrotic syndrome
Am J Physiol Renal Physiol. 2002 Sep;283(3):F464-72.

Del Ry et al. Increased levels of C-type natriuretic peptide in patients with idiopathic left ventricular dysfunction
Peptides. 2007 May;28(5):1068-73.

Klinger et al. C-type natriuretic peptide expression and pulmonary vasodilation in hypoxia-adapted rats.
Am J Physiol. 1998 Oct;275(4 Pt 1):L645-52

Herten - Nephrol. Dial. Transplant - (1998) 13: 2529