Brain Natriuretic Peptides (BNP)

Normal Plasma Peptide/Protein Levels

Protocol	Assay Protocol (PDF)
Sample Preparation	Blood collection Plasma extraction Tissue extraction CSF extraction
Catalog #	RK-011-10
Standard Size	125 RIA tubes
Radioactivity	This kit contains 1.5 µCi of Iodine 125
Range	1-128 pg/tube in 100μl of Standard Solution = 10-1280 pg/ml
Lowest Detection Limit	47.1 pg/ml
Cross Reactivity	Peptide %Cross-reactivity  BNP-32 (Porcine)  100  BNP-26 (Porcine)  100  BNP-32 (Canine)  81  BNP-32 (Human)  0  BNP-32 (Rat)  0  α-ANP (1-28) (Human, Canine)  0  CNP-22 (Human, Porcine, Rat)  0  Endothelin-1 (Human, Bovine, Canine, Mouse, Porcine, Rat)  0
Sequence	Ser - Pro - Lys - Thr - Met - Arg - Asp - Ser - Gly - Cys - Phe - Gly - Arg - Arg - Leu - Asp - Arg - Ile - Gly - Ser - Leu - Ser - Gly - Leu - Gly - Cys - Asn - Val - Leu - Arg - Arg - Tyr ~ Disulfide Bridge between Cys10 & Cys26

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this kit:

Goetze et al. Acute myocardial hypoxia increases BNP gene expression
FASEB J. 2004 Dec;18(15):1928-30.

Jayachandran et al. Sex-specific changes in platelet aggregation and secretion with sexual maturity in pigs.
J Appl Physiol. 2004 Oct;97(4):1445-52.

Thomas et al. Haemodynamic action of B-type natriuretic peptide substantially outlasts its plasma half-life in conscious dogs.
Clin Exp Pharmacol Physiol. 2003 May-Jun;30(5-6):369-75.

Brunner-La Rocca et al. Divergent effects of ANP and BNP in acute heart failure: evidence for a putative BNP-selective receptor?
J Hypertens. 2002 Jun;20(6):1195-201. 

Woods et al. Atrial, B-type, and C-type natriuretic peptides cause mesenteric vasoconstriction in conscious dogs.
Am J Physiol. 1999 May;276(5 Pt 2):R1443-52.

Woods - Regl. - Integr. And Comparative Phys. - Vol. 276 - Issue 5 - R1443-R1452 - May 1999