Secretin

Normal Plasma Peptide/Protein Levels

Antibody Production & Evaluation

Catalog #	H-067-03
Standard Size	50 µl
Sequence	His - Ser - Asp - Gly - Thr - Phe - Thr - Ser - Glu - Leu - Ser - Arg - Leu - Arg - Glu - Gly - Ala - Arg - Leu - Gln - Arg - Leu - Leu - Gln - Gly - Leu - Val - NH2
Species	Human
Host	Rabbit
Reconstitution	For consistent and reproducible results, reconstitute with 50µl of distilled water for the equivalent of undiluted antiserum, immediately before use. Do not refreeze any unused portions.
Storage Condition	Please store the lyophilized antibody at -20°C upon receipt. For optimal results, use the antibody immediately after reconstitution. Once reconstituted, the antibody is stable for up to three (3) days at 4°C. For longer-term storage up to three (3) months, prepare small aliquots of the reconstituted antibody and freeze at -20°C or -80°C. Repeated freeze-thaw cycles should be strictly avoided.
Content	This vial contains 50µl of Rabbit Anti-Secretin (Human) Serum in the lyophilized form.
Recommended Dilution Factor	Immunofluorescence: 1:200 PAP or ABC: 1:500
Cross Reactivity	Peptide  % Cross-reactivity  Secretin (Human)  100  Secretin (Porcine)  100  Substance P  0  CCK (26-33) (Non-sulfated)  0  Insulin (Human)  0  NPY (Porcine)  0  VIP (Human, Porcine, Rat)  0  Somatostatin  0

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this antibody:

Vanhorenbeeck et al. Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation
Dev Biol. 2007 May 15;305(2):685-94.

Lee et al. Retinoic acid activates human secretin gene expression by Sp proteins and nuclear factor I in neuronal SH-SY5Y cells.
J Neurochem. 2005 Apr;93(2):339-50.

Lee et al. Expression and spatial distribution of secretin and secretin receptor in human cerebellum.
Neuroreport. 2005 Feb 28;16(3):219-22.

Siu et al. Secretin, a known gastrointestinal peptide, is widely expressed during mouse embryonic development.
Gene Expr Patterns. 2005 Feb;5(3):445-51.

Lee et al. Regulation of the human secretin gene is controlled by the combined effects of CpG methylation, Sp1/Sp3 ratio, and the E-box element.
Mol Endocrinol. 2004 Jul;18(7):1740-55.