Corticotropin Releasing Factor (CRF)

Catalog #	019-16
Standard Size	200 µg
Sequence	Asp - Leu - Thr - Phe - His - Leu - Leu - Arg - Glu - Met - Leu - Glu - Met - Ala - Lys - Ala - Glu - Gln - Glu - Ala - Glu - Gln - Ala - Ala - Leu - Asn - Arg - Leu - Leu - Leu - Glu - Glu - Ala - NH2
Species	Ovine
M.W	3826.43
Mass Spec Analysis	Exhibits correct M.W.
Solubility	Insoluble in water. Re-hydrate the content with 100-500µl of pH >9 0.1M ammonium hydroxide or any other basic buffer.
Storage Condition	Store peptide in DRY form at 0-5°C.
Appearance	White powder
Content	The contents of this vial have been accurately determined to contain 200µg of NET peptide.
HPLC Analysis	Purity ≥95%
Additional articles	For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this product:

Charron et al. In vivo administration of corticotropin-releasing hormone at remote intervals following ischemia enhances CA1 neuronal survival and recovery of spatial memory impairments: A role for opioid receptors
Behav Brain Res. 2008 Mar 17;188(1):125-35.

Lebrethon et al. Effects of In Vivo and In Vitro Administration of Ghrelin, Leptin and Neuropeptide Mediators on Pulsatile Gonadotrophin-Releasing Hormone Secretion from Male Rat Hypothalamus Before and After Puberty
J Neuroendocrinol. 2007 Mar;19(3):181-8.

Tu et al. Corticotropin-Releasing Hormone Receptor (CRHR)1 and CRHR2 Are Both Trafficking and Signaling Receptors for Urocortin
Mol Endocrinol. 2007 Mar;21(3):700-11.

Plamondon et al. The CRH1 antagonist CP154,526 failed to alter ischemia-induced neurodegeneration and spatial memory deficits in rats but inhibited behavioral activity in the novel open field.
Behav Brain Res. 2006 Jan 6;166(1):85-92.

Samson et al. Prolactin-releasing peptide and its homolog RFRP-1 act in hypothalamus but not in anterior pituitary gland to stimulate stress hormone secretion.
Endocrine. 2003 Feb-Mar;20(1-2):59-66.

Correia et al. Role of corticotrophin-releasing factor in effects of leptin on sympathetic nerve activity and arterial pressure.
Hypertension. 2001 Sep;38(3):384-8.

Leitch et al. Vasodilator Actions of Urocortin and Related Peptides in the Human Perfused Placenta in Vitro
J Clin Endocrinol Metab. 1998 Dec;83(12):4510-3.

For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.