Calcitonin Gene Related Peptide (CGRP)

Normal Plasma Peptide/Protein Levels

Catalog #	015-02
Standard Size	200 µg
Sequence	Ala - Cys - Asp - Thr - Ala - Thr - Cys - Val - Thr - His - Arg - Leu - Ala - Gly - Leu - Leu - Ser - Arg - Ser - Gly - Gly - Val - Val - Lys - Asn - Asn - Phe - Val - Pro - Thr - Asn - Val - Gly - Ser - Lys - Ala - Phe - NH2 Disulfide Bridge: Cys2 - Cys7
Species	Human
M.W	3789.35
Mass Spec Analysis	Exhibits correct M.W.
Solubility	Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition	Store peptide in DRY form at 0-5°C.
Appearance	White powder
Content	The contents of this vial have been accurately determined to contain 200µg of NET peptide.
HPLC Analysis	Purity ≥95%
Additional articles	For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this peptide:

Tam et al. Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2.
Circ Res. 2006 Feb 3;98(2):262-70.

Linscheid et al. Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue.
Endocrinology. 2005 Jun;146(6):2699-708.

Li et al. Stress-induced suppression of the gonadotropin-releasing hormone pulse generator in the female rat: a novel neural action for calcitonin gene-related peptide.
Endocrinology. 2004 Apr;145(4):1556-63.

Tam et al. The assessment of vasoactive properties of CGRP and adrenomedullin in the microvasculature: a study using in vivo and in vitro assays in the mouse.
J Mol Neurosci. 2004;22(1-2):117-24.

Thomson et al. Autocrine role of adrenomedullin in the human adrenal cortex.
J Endocrinol. 2001 Jul;170(1):259-65.

Pio et al. Complement factor H is a serum-binding protein for adrenomedullin, and the resulting complex modulates the bioactivities of both partners.
J Biol Chem. 2001 Apr 13;276(15):12292-300.

Carucci et al. Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell-proliferative responses via the type I calcitonin gene-related peptide receptor.
J Immunol. 2000 Apr 1;164(7):3494-9.

For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.