Brain Natriuretic Peptides (BNP)

Normal Plasma Peptide/Protein Levels

Catalog #	011-22
Standard Size	200 µg
Sequence	Ser - Pro - Lys - Met - Met - His - Lys - Ser - Gly - Cys - Phe - Gly - Arg - Arg - Leu - Asp - Arg - Ile - Gly - Ser - Leu - Ser - Gly - Leu - Gly - Cys - Asn - Val - Leu - Arg - Lys - Tyr Disulfide Bridge: Cys10 - Cys26
Species	Canine
M.W	3566.29
Mass Spec Analysis	Exhibits correct M.W.
Solubility	Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition	Store peptide in DRY form at 0-5°C.
Appearance	White powder
Content	The contents of this vial have been accurately determined to contain 200µg of NET peptide.
HPLC Analysis	Purity ≥95%
Additional articles	For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this peptide:

Schellenberg et al. Analytical validation of commercial immunoassays for the measurement of cardiovascular peptides in the dog.
Vet J. 2008 Oct;178(1):85-90.

Forfia et al. Acute Phosphodiesterase 5 Inhibition Mimics Hemodynamic Effects of B-Type Natriuretic Peptide and Potentiates B-Type Natriuretic Peptide Effects in Failing But Not Normal Canine Heart
J Am Coll Cardiol. 2007 Mar 13;49(10):1079-88.

Chen et al. Maximizing the renal cyclic 3'-5'-guanosine monophosphate system with type V phosphodiesterase inhibition and exogenous natriuretic peptide: a novel strategy to improve renal function in experimental overt heart failure.
J Am Soc Nephrol. 2006 Oct;17(10):2742-7.

Tsuruda et al. Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases.
Circ Res. 2002 Dec 13;91(12):1127-34.
For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.