Adrenomedullin

Normal Plasma Peptide/Protein Levels

Adrenomedullin-5 Porcine

Catalog #	010-04
Standard Size	100 µg
Sequence	Thr - Val - Gln - Lys - Leu - Ala - His - Gln - Ile - Tyr - Gln - Phe - Thr - Asp - Lys - Asp - Lys - Asp - Asn - Val - Ala - Pro - Arg - Ser - Lys - Ile - Ser - Pro - Gln - Gly - Tyr - NH2
Species	Human
M.W	3576.03
Mass Spec Analysis	Exhibits correct M.W.
Solubility	Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition	Store peptide in DRY form at 0-5°C. For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.
Appearance	White powder
Content	The contents of this vial have been accurately determined to contain 100µg of NET peptide.
HPLC Analysis	Purity > 95%

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this peptide:

Deng, Boya et al., Adrenomedullin expression in epithelial ovarian cancers and promotes HO8910 cell migration associated with upregulating integrin α5β1 and phosphorylating FAK and paxillin.
Journal of Experimental & Clinical Cancer Research, March 9, 2012

Zeng et al. Upregulated expression of intermedin and its receptor in the myocardium and aorta in spontaneously hypertensive rats.
Peptides. 2009 Feb;30(2):391-9.

Allaker et al. Interaction ofadrenomedullin and calcitonin gene-related peptide with the periodontal pathogen Porphyromonas gingivalis
FEMS Immunol Med Microbiol. 2007 Feb;49(1):91-7.

Pan et al. The myocardial response to adrenomedullin involves increased cAMP generation as well as augmented Akt phosphorylation
Peptides. 2007 Apr;28(4):900-9.

Allaker et al. Mechanisms of adrenomedullin antimicrobial action.
Peptides. 2006 Apr;27(4):661-6.

Zudaire et al. Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis.
Am J Pathol. 2006 Jan;168(1):280-91.

Ren et al. Intermedin 1-53 in central nervous system elevates arterial blood pressure in rats.
Peptides. 2006 Jan;27(1):74-9.

Linscheid et al. Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue.
Endocrinology. 2005 Jun;146(6):2699-708.

Jiang et al. Effects of adrenomedullin on cell proliferation in rat adventitia induced by aldosterone.
J Hypertens. 2004 Oct;22(10):1953-61.

Juaneda et al. Adrenomedullin receptor binding sites in rat brain and peripheral tissues.
Eur J Pharmacol. 2003 Aug 8;474(2-3):165-74. 

Ornan et al. Saturation of adrenomedullin receptors plays an important role in reducing pulmonary clearance of adrenomedullin during the late stage of sepsis.
Biochim Biophys Acta. 2002 Apr 24;1586(3):299-306.