Catalog #	023-51
Standard Size	500 µg
Sequence	Homopiperidinyl - carbonyl - Leu - D - Trp(CHO) - D - Trp
M.W	656.78
Mass Spec Analysis	Exhibits correct M.W.
Solubility	Insoluble in water. Re-hydrate content with at least 100-200µl of organic solvent such as DMSO or Acetonitrile.
Storage Condition	Store peptide in DRY form at 0-5°C.
Appearance	White powder
Content	The contents of this vial have been accurately determined to contain 500µg of NET peptide.
HPLC Analysis	Purity ≥95%
Additional articles	For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this peptide:

Juan et al. Endothelin-1 Regulates Adiponectin Gene Expression and Secretion in 3T3-L1 Adipocytes via Distinct Signaling Pathways
Endocrinology. 2007 Apr;148(4):1835-42.

Kwok et al. Endothelin-1 decreases CD36 protein expression in vascular smooth muscle cells
Am J Physiol Endocrinol Metab. 2007 Feb;292(2):E648-52.

Juan et al. Endothelin-1 induces lipolysis in 3T3-L1 adipocytes.
Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1146-52.

Liu et al. Prior antagonism of endothelin-1A receptors alleviates circulatory shock and cerebral ischemia during rat heatstroke.
J Pharmacol Sci. 2004 Oct;96(2):177-87.

Beyer et al. ET(A) receptor blockade improves post-ischaemic functional recovery in 'hibernating' rat myocardium.
Clin Sci (Lond). 2002 Aug;103 Suppl 48:215S-218S.

Liang et al. Endothelin-dependent and -independent components of strain-activated brain natriuretic peptide gene transcription require extracellular signal regulated kinase and p38 mitogen-activated protein kinase.
Hypertension. 2000;35:188

Beyer et al. Inotropic effects of endothelin-1: interaction with molsidomine and with BQ 610.
Hypertension. 1999;33:145-152 

Other Information:

30 times more potent than BQ-123 in porcine aortic smooth muscle membrane assay, same activity as BQ-123 when tested in porcine cerebellum membranes - K. Ishikawa et al., Peptides 1992, Schneider and Eberle, ed. (ESCOM), p.685.

For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.