Pro-MCH Precursor Sequence - Human

Normal Plasma Peptide/Protein Levels

Catalog #	071-20
Standard Size	100 µg
Species	Human

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MCH receptor termed MCH-2R, shares about 38% amino acid identity with MCH-1R. MCH-2R displayed high-affinity MCH binding, resulting in inositol phosphate turnover and release of intracellular calcium in mammalian cells. In contrast to MCH-1R, MCH-2R signaling is not sensitive to pertussis toxin and MCH-2R cannot reduce forskolin-stimulated cAMP production, suggesting an exclusive G(alpha)q coupling of the MCH-2R in cell-based systems - Sailer et al. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7564-9.