Urotensin II

Catalog #	071-05
Standard Size	500 µg
Sequence	Glu - Thr - Pro - Asp - Cys - Phe - Trp - Lys - Tyr - Cys - Val ~ Disulfide Bridge between Cys5 & Cys10
Species	Human
M.W	1388.56
Mass Spec Analysis	Exhibits correct M.W.
Solubility	Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition	Store peptide in DRY form at 0-5°C.
Appearance	White powder
Content	The contents of this vial have been accurately determined to contain 500µg of NET peptide.
HPLC Analysis	Purity ≥95%
Additional articles	For best results and reproducibility, rehydrate peptide just before use. Do not refreeze any unused portions. Do not attempt to weigh out smaller portions.

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this peptide:

Holleran et al. Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites
Biochem J. 2007 Feb 15;402(1):51-61.

Kemp et al. Urotensin II: a novel vasoactivemediator linked to chronic liver disease and portal hypertension
Liver Int. 2007 Nov;27(9):1232-9.

Joyal et al. Urotensin-II levels in acute coronary syndromes.
Int J Cardiol. 2006 Mar 22;108(1):31-5.

Rademaker et al. Endogenous urocortins reduce vascular tone and renin-aldosterone/endothelin activity in experimental heart failure.
Eur Heart J. 2005 Oct;26(19):2046-54.

Qi et al. Characterization of functional urotensin II receptors in human skeletal muscle myoblasts: comparison with angiotensin II receptors.
Peptides. 2005 Apr;26(4):683-90.

Brailoiu et al. The vasoactive peptide urotensin II stimulates spontaneous release from frog motor nerve terminals.
Br J Pharmacol. 2003 Apr;138(8):1580-8.

Rademaker et al. Beneficial hemodynamic, endocrine, and renal effects of urocortin in experimental heart failure: comparison with normal sheep.
J Am Coll Cardiol. 2002 Oct 16;40(8):1495-505.

For best results and reproducibility, rehydrate peptide just before use. Do not refreeze any unused portions. Do not attempt to weigh out smaller portions.