Substance P (Human, Rat, Mouse)

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Substance P (Human, Rat, Mouse)

Catalog#	Standard size	Price	Order
061-05	500 µg	$27.00

Catalog #	061-05
Standard Size	500 µg
Sequence	Arg - Pro - Lys - Pro - Gln - Gln - Phe - Phe - Gly - Leu - Met - NH2
Species	Human, Rat, Mouse
M.W	1347.65
Mass Spec Analysis	Exhibits correct M.W.
Solubility	Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition	Store peptide in DRY form at 0-5°C.
Appearance	White powder
Content	The contents of this vial have been accurately determined to contain 500µg of NET peptide.
HPLC Analysis	Purity ≥95%
Additional articles	For best results and reproducibility, rehydrate peptide just before use. Do not refreeze any unused portions. Do not attempt to weigh out smaller portions.

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Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this peptide:

Pailleux F, Lemoine J, Beaudry F. Investigation of the metabolic biotransformation of substance P in liver microsomes by liquid chromatography quadrupole ion trap mass spectrometry.
Biomedical Chromatography. 2013;27(1):39-47.

Vachon P, Millecamps M, Low L, et al. Alleviation of chronic neuropathic pain by environmental enrichment in mice well after the establishment of chronic pain.
Behavioral & Brain Functions. 2013;9:22.

Pailleux F, Vachon P, Lemoine J, Beaudry F. Targeted liquid chromatography quadrupole ion trap mass spectrometry analysis of tachykinin related peptides reveals significant expression differences in a rat model of neuropathic pain.
Neuropeptides. 2013;47(4):261-71.

Pailleux F, Lemoine J, Beaudry F. Quantitative mass spectrometry analysis reveals that deletion of the TRPV1 receptor in mice alters substance P and neurokinin A expression in the central nervous system.
Neurochemical Research. 2012;37(12):2678-85.

Beaudry et al. Early dexamethasone treatment after implantation of a sciatic-nerve cuff decreases the concentration of substance P in the lumbar spinal cord of rats with neuropathic pain
Can J Vet Res. 2007 Apr;71(2):90-7.

Caviedes-Bucheli et al. Substance P receptor expression in healthy and inflamed human pulp tissue
Int Endod J. 2007 Feb;40(2):106-11.

Beaudry et al. Determination of substance P in rat spinal cord by high-performance liquid chromatography electrospray quadrupole ion trap mass spectrometry.
Biomed Chromatogr. 2006 Dec;20(12):1344-50.

Zudaire et al. Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis.
Am J Pathol. 2006 Jan;168(1):280-91.

Zhang et al. Tachykinin agonists modulate cholinergic neurotransmission at guinea-pig intracardiac Ganglia.
J Pharmacol Sci. 2005 Nov;99(3):228-38.

Berger et al. Hemokinin-1 has Substance P-like function in U-251 MG astrocytoma cells: a pharmacological and functional study.
J Neuroimmunol. 2005 Jul;164(1-2):48-56.

Chen et al. Termination of protease-activated receptor-1 signaling by beta-arrestins is independent of receptor phosphorylation.
J Biol Chem. 2004 Mar 12;279(11):10020-31.

Katki et al. Substance P in subtotal nephrectomy-salt hypertension.
Hypertension. 2002 Feb;39(2 Pt 2):389-93.

Howard et al. Identification of receptors for neuromedin U and its role in feeding.
Nature. 2000 Jul 6;406(6791):70-4.

For best results and reproducibility, rehydrate peptide just before use. Do not refreeze any unused portions. Do not attempt to weigh out smaller portions.