Alpha-MSH (Alpha-Melanocyte Stimulating Hormone)

Catalog #	043-06
Standard Size	500 µg
Sequence	Ac - Ser - Tyr - Ser - Nle - Glu - His - D - Phe - Arg - Trp - Gly - Lys - Pro - Val - NH2
M.W	1645.85
Mass Spec Analysis	Exhibits correct M.W.
Solubility	Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition	Store peptide in DRY form at 0-5°C.
Appearance	White powder
Content	The contents of this vial have been accurately determined to contain 500µg of NET peptide.
HPLC Analysis	Purity ¡Ý95%
Additional articles	For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this peptide:

Fan et al. Pharmacological analyses of two naturally occurring porcine melanocortin-4 receptor mutations in domestic pigs
Domest Anim Endocrinol. 2008 May;34(4):383-90.

Vulliémoz et al. Melanocortin modulation of inflammatory cytokine and neuroendocrine responses to endotoxin in the monkey.
Endocrinology. 2006 Apr;147(4):1878-83.

Tao et al. Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation.
J Clin Endocrinol Metab. 2004 Aug;89(8):3936-42.

Donohoue et al. Deletion of codons 88-92 of the melanocortin-4 receptor gene: a novel deleterious mutation in an obese female.
J Clin Endocrinol Metab. 2003 Dec;88(12):5841-5.

Zeh et al. Gain-of-function somatic cell lines for drug discovery applications generated by homologous recombination.
Assay Drug Dev Technol. 2003 Dec;1(6):755-65.

Xiao et al. Agouti-Related Protein Stimulates the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Enhances the HPA Response to Interleukin-1 in the Primate
Endocrinology. 2003 May;144(5):1736-41.

Other Information:

Very potent melanotropin with prolonged biological activity and resistance to degradation by serum enzymes - T. K. Sawyer et al., PNAS 77, 5754 (1980).

For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.