Alpha-MSH (Alpha-Melanocyte Stimulating Hormone)

Catalog #	043-01
Standard Size	500 µg
Sequence	Ac - Ser - Tyr - Ser - Met - Glu - His - Phe - Arg - Trp - Gly - Lys - Pro - Val - NH2
Species	Human, Rat, Mouse
M.W	1664.91
Mass Spec Analysis	Exhibits correct M.W.
Solubility	Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition	Store peptide in DRY form at 0-5°C.
Appearance	White powder
Content	The contents of this vial have been accurately determined to contain 500µg of NET peptide.
HPLC Analysis	Purity ≥96%
Additional articles	For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this peptide:

 

 

Fan Yang, Ya-Xiong Tao, Functional characterization of nine novel naturally occurring human melanocortin-3 receptor mutations. 
Biochim Biophys Acta. 2012 Nov;1822(11):1752-61. doi: 10.1016/j.bbadis.2012.07.017. Epub 2012 Aug 3. 

Praful S. Singru, Gábor Wittmann, Erzsébet Farkas, et al, Refeeding-Activated Glutamatergic Neurons in the Hypothalamic Paraventricular Nucleus (PVN) Mediate Effects of Melanocortin Signaling in the Nucleus Tractus Solitarius (NTS). 
Endocrinology 2012 153: 3804-3814; doi:10.1210/en.2012-1235

Olszewski et al. alpha-Melanocyte stimulating hormone and ghrelin: Central interaction in feeding control
Peptides. 2007 Oct;28(10):2084-9.

Bomberg et al. Functional interaction between nociceptin/orphanin FQ and alpha-melanocyte-stimulating hormone in the regulation of feeding.
Peptides. 2006 Jul;27(7):1827-34.

Helwig et al. PC1/3 and PC2 gene expression and post-translational endoproteolytic pro-opiomelanocortin processing is regulated by photoperiod in the seasonal Siberian hamster (Phodopus sungorus).
J Neuroendocrinol. 2006 Jun;18(6):413-25.

Kim et al. C-terminal part of AgRP stimulates insulin secretion through calcium release in pancreatic beta Rin5mf cells.
Neuropeptides. 2005 Aug;39(4):385-93.

Zou et al. Alpha-melanocyte stimulating hormone protects against H2O2-induced inhibition of wound restitution in IEC-6 cells via a Syk kinase- and NF-kappabeta-dependent mechanism.
Shock. 2004 Nov;22(5):453-9.

Sasaki et al. Suppression of melanogenesis by induction of endogenous intracellular metallothionein in human melanocytes.
Exp Dermatol. 2004 Aug;13(8):465-71.

Zeh et al. Gain-of-function somatic cell lines for drug discovery applications generated by homologous recombination.
Assay Drug Dev Technol. 2003 Dec;1(6):755-65.

Lassalle et al. Effects of melanogenesis-inducing nitric oxide and histamine on the production of eumelanin and pheomelanin in cultured human melanocytes.
Pigment Cell Res. 2003 Feb;16(1):81-4.

Kim et al. Effects of melanocortin receptor ligands on thyrotropin-releasing hormone release: evidence for the differential roles of melanocortin 3 and 4 receptors.
J Neuroendocrinol. 2002 Apr;14(4):276-82. 

Howard et al. Identification of receptors for neuromedin U and its role in feeding.
Nature. 2000 Jul 6;406(6791):70-4.

Kwon et al. Reduced abundance of aquaporins in rats with bilateral ischemia-induced acute renal failure: prevention by alpha-MSH 
Am J Physiol. 1999 Sep;277(3 Pt 2):F413-27.

Chiao et al. Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats.
J Clin Invest. 1997 Mar 15;99(6):1165-72.

For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.

 

 

For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.