Hinuma, S., et al. The quest for novel bioactive
peptides utilizing orphan seven-membrane-domain receptors. Journal of Molecular Medicine 77, 495-504 (1999)
Ames,
R.S., et al. Human urotensin II is a potent vasoconstrictor and agonist
for the orphan receptor GPR14. Nature 401, 282-286 (1999)
Nothacker,
H.-P. et al., Identification of the natural ligand of an orphan G-protein-coupled
receptor involved in the regulation of vasoconstriction. Nature
Cell Biology 1, 383-385 (1999)
Chambers,
J. et al., Melanin-concentrating hormone is the cognate ligand for
the orphan G-protein-coupled receptor SLC-1. Nature 400, 261-265 (1999)
Hinuma,
S. et al., Molecular cloning and functional expression of a human
thyrotropin-releasing hormone (TRH) receptor gene. Biochemica Biophysica
acta 1219, 251-259 (1994)
Fujii,
R., et al. Tissue distribution of prolactin-releasing peptide (PrRP)
and its receptor. Regulatory Peptides (1999, in press)
Lecea,
L., et al. The hypocretins: hypothalamus-specific peptides with neuroexcitatory
activity. PNAS 95, 322-327 (1998)
Sakurai,
T.S., et al. Orexins and orexin receptors: a family of hypothalamic
neuropeptides and G protein-couples receptors that regulate feeding
behavior. cell 92,573-585(1998)
Tatemoto
K., et al. isolation and characterization of a novel endogenous peptide
ligand for the human APJ receptor. Biochem Biophys Res Commun 251,
471-476 (1998)
Meunier,
J-C., et al. Isolation and structure of the endogenous agonist of
opioid receptor-like ORL1 receptor. Nature 377,532-535(1995)
Reinscheid,
R. K., et al. Orphanin FQ: A neuropeptide that activates an opioid-like
G protein -coupled receptor. Science 270,792-794(1995)
Cox,
K. J.A. et al. Cloning, characterization, and expression of a G-protein-coupled
receptor from Lymnaea stagnails and identification of a leucokinin-like
peptide, FSFHSWSamide, as its endogenous ligand. J Neurosci 17,1197-1205(1997)
Tensen,
C. P., et al. The Lymnaea cardioexcitatory peptide (LyCEP) receptor:
a G-protein-coupled receptor for a novel member of the Rfamide neuropeptide
family. J Neurosci 18,9812-9821(1998)
Liu,
Q., et al. Identification of urotensin II as the endogenous ligand
for the orphan G-protein-coupled receptor GPR14.Biochem Biophys
Res Commun 266,174-178(1999)
Mori, M., et al. Urotensin II is the endogenous
ligand of a G-protein-coupled orphan receptor, SENR (GP R14).Biochem
Biophys Res Commun. 265, 123-129(1999).
Lembo,
P. M., et al.The receptor for the orexigenic peptide melanin-concentrating
hormone is a G-protein-coupled receptor. Nat Cell Biolog. 1, 267-271(1999)
Habata,
Y., et al. Apelin, the natural ligand of the orphan receptor APJ,
is abundantly secreted in the colostrum.
Biochim Biophys Acta. 1452, 25-35(1999)
Kojima,
M., et al. Ghrelin is a growth-hormone-releasing acylated peptide
from stomach. Nature 402,656-660(1990)
Ohtaki,
T, et al. Isolation and cDNA cloning of a novel galanin-like peptide
(GALP) from porcine hypothalamus. J Biol Chem 274,37041-37045(1990)
Usdin,
T.B. et al. TIP39: a new neuropeptide and PTH2-receptor agonist from
hypothalamus. Nat Neurosci 2,941-943(1990)
Elshourbagy
N.A., et al. Receptor for the Pain Modulatory Neuropeptides NPFF and
NPAF is an Orphan G-Protein-Coupled Receptor. JBC (June 12, 2000)
Szekeres,
P.G., et al. Neuromedin U is a potent agonist at the orphan G protein
coupled receptor FM3. JBC (May 12, 2000)
Fujii
R., et al. Identification of Neuromedin U as the cognate ligand of
the orphan G protein-coupled receptor FM-3. JBC (April 26, 2000)
Feighner
SD, et al. Receptor for motilin identified in the human gastrointestinal
system. Science 1999 Jun 25;284(5423):2184-8.